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istradefylline will improve the amount or outcome of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
nilotinib will increase the amount or effect of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
acetazolamide will boost the level or result of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Not known.
Reserve concomitant use for sufferers in whom alternate procedure selections are inadequate; use cheapest helpful dosages and shortest achievable duration of concomitant therapy and observe closely for respiratory despair and sedation. (See Particular Prescription drugs and Laboratory Assessments underneath Interactions.)
An individual who's got consumed excessive diazepam usually shows a number of of those signs in the duration of about four hours instantly adhering to a suspected overdose:[37][88]
You might want to get Valium out of your method if you are dealing with uncomfortable Unwanted effects or if your medical professional is intending to switch you to another check here medication.
The metabolites with the drug could have A great deal longer half-lives likewise. Nordiazepam, by way of example, incorporates a fifty click here percent-lifetime of approximately one hundred hrs. Valium also accumulates when folks acquire a number of doses about a time period, which might slightly prolong the entire 50 %-life of the compound.
miconazole vaginal will enhance the degree or influence more info of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
Get clinical help at once if you cease utilizing diazepam and have symptoms for example: uncommon muscle actions, becoming extra active or talkative, sudden and severe alterations in mood or actions, confusion, hallucinations, seizures, or feelings about suicide.
If you frequently overlook doses, it may well support to established an alarm to remind you. You might also request your pharmacist for suggestions on other methods to make sure to just take your medicine.
sage decreases outcomes of diazepam by pharmacodynamic antagonism. Slight/Importance Unfamiliar. Theoretical interaction; some species of sage may perhaps induce convulsions.
Helpful remedies might involve tapering your dosage to control withdrawal signs and psychotherapeutic approaches like cognitive-behavioral therapy and contingency administration.
diazepam will increase toxicity of oliceridine by Other (see remark). Modify Therapy/Monitor Closely. Remark: Anticholinergic medications may well enhance hazard of urinary retention and/or severe constipation, which may result in paralytic ileus.